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Doctors who specialize in cancer treatment determine what kind of treatment to prescribe with their patient. The options are endless. There exists no regular treatment regimen for peritoneal mesothelioma cancer sufferers. This is due to the cancers high mortality rate, rareness, low treatment success rate, and small number of studies to provide meaningful statistics.

Mesothelioma patients have historically had a bleak outlook, but doctors have recently made progress. Customary treatments for cancer are surgery (removing the tumor and the tissue that surrounds it), chemotherapy (poisoning cancerous cells) and radiation (killing cancer cells with radiation) All three methods have problems. Traditional radiation therapy has not worked well with mesothelioma patients. In hopes to lessen damage to healthy tissue, researches are studying ways to aim radiation right at the tumor.

Surgery removes the mesothelial tissue around the tumor. It is a grueling surgery with unknown benefits to patients. Most chemotherapy medication that work on other cancers typically do not work on mesothelioma, and different mixtures of these drugs have not been successful. Like radiation, researchers are focusing their work on controlling the physical location of the treatment with an emphasis on the pleural cavity.

Many advanced techniques in cancer treatment are tried on mesothelioma patients because of its high fatality rate. These include biologic therapy such as the agent interleukin 2 and anti-angiogenesis drugs such as thalidomide. Pemetrexed (Alimta) is a new drug that has shown results in extending life.

Considered by oncologists is where the tumor is located, what stage the mesothelioma is in, and the age and health of the patient. Two therapies that are extremely cutting-edge in fighting cancer are called photodynamic and gene therapy. Mesothelioma patients sometimes become involved in clinical trials in this area, and see benefits.